Our Advisory Committee
MD, PhD, FRCP(C)
Dr. Annie Huang is a Senior Neuro-Oncologist with the Paediatric Brain Tumour Program at The Hospital for Sick Children, Toronto, where she also holds appointments as Senior Scientist in Cell Biology, and Principal Investigator at the Arthur and Sonia Labatt Brain Tumour Research Centre. She is an Associate Professor in the Departments of Paediatrics, Lab Medicine and Pathobiology at the University of Toronto, Canada. Dr. Huang's laboratory work aims to elucidate the molecular pathogenesis of rare malignant paediatric embryonal brain tumours, including CNS-PNETs and Atypical Teratoid Rhabdoid tumours. Dr. Huang's research combines a laboratory interest in molecular pathogenesis of EBTs, with a clinical translational interest in infant brain tumours.
MBChB, PhD, FRACP
Dr. Nick Gottardo is a Senior Paediatric Oncologist at the Princess Margaret Hospital for Children in Perth, Australia. He also co-leads the Brain Tumour Program in the Division of Children's Leukaemia and Cancer Research of the Telethon Kids Institute. Dr. Gottardo and his team employ high-throughput robotics to generate sophisticated laboratory models using brain cancer cells obtained from patients at the time of surgery. Dr, Gottardo's research aims to expedite the translation of drugs discovered in his program into new treatments for childhood brain cancer
BScH, MSc, MBBS, FRACP
Dr. Jordan Hansford is a pediatric oncologist at the Solid and Brain Tumour Division of The Royal Children's Hospital in Melbourne, Australia. He is on the Consultant Medical Staff for Solid Tumours and Neuro Oncology. Dr. Hansford has a keen research interest in cancer genetics, and rare brain tumors, including low-grade gliomas and medulloblastomas.
Dr. Eric Bouffet is a Professor of Paediatrics at the University of Toronto. He is the Head of the Neuro-Oncology Section in the Division of Haematology/Oncology at The Hospital for Sick Children in Toronto, Canada. He is the past chair of the Brain Tumour Group with the International Society of Pediatric Oncology (SIOP), and he is the new elected President of the SIOP. Dr. Bouffet's research interests are in the area of novel treatments and clinical trials in children with brain tumours. He has developed multiple clinical studies for low-grade gliomas. He also has a special interest in providing neuro-oncology in developing countries, including Jordan, Pakistan, and Saudi Arabia.
Dr. Amar Gajjar is the director of the Neuro-Oncology Division at St. Jude Children's Research Hospital in Memphis, Tennessee and he is the Scott and Tracie Hamilton Endowed Chair in Brain Tumor Research. He is a co-chair for the Department of Oncology of St. Jude's Children Research Hospital, a co-leader of the Neurobiology and Brain Tumour Program, and the Interim Chair for the Department of Pediatric Medicine. Dr. Gajjar is also the chair of the Central Nervous System Disease Committee of the Children's Oncology Group, the largest paediatric clinical trial network. Dr. Gajjar's current clinical research interests focus on innovative protocols for the treatment of childhood brain tumours, with a particular regard for medulloblastomas, PNETs, and Rhabdoid tumours. Dr. Gajjar and his team work to develop new chemotherapeutic agents for the treatment of brain tumours and unravel the mechanisms by which key anticancer drugs work.
Dr. Lucie Lafay-Cousin is a Paediatric Oncologist in the Department of Neuro-Oncology at The Alberta Children's Hospital. She is also an Associate Professor in the Faculty of Medicine at the University of Calgary in Alberta, Canada. Dr. Lafay-Cousin's primary research interests include paediatric brain tumours, infant medulloblastomas, atypical teratoid rhabdoid tumours, and long term follow up of pediatric brain tumor survivors.
MD, PhD, FRCPC
Dr. Hawkins is a paediatric neuropathologist at The Hospital for Sick Children in Toronto, where she also holds positions as Senior Scientist in Cell Biology and Principal Investigator at The Arthur and Sonia Labatt Brain Tumour Research Centre. She is also a Professor in the Department of Laboratory Medicine & Pathobiology at the University of Toronto, Canada. Dr. Hawkins' practice involves both surgical and autopsy neuropathology, and includes neuro-oncologic, neuromuscular, and neurodevelopmental disease. Her research interests focus on molecular pathogenesis and therapeutics for paediatric astrocytomas, in particular diffuse intrinsic pontine glioma (DIPG). Dr. Hawkins and her team also conduct research on the identification and clinical implementation of novel prognostic and therapeutic markers for paediatric brain tumours.
Dr. Barry Pizer is a Consultant Paediatric Oncologist at the Alder Hey Children's Hospital, UK and he is an Honourary Professor at the University of Liverpool. He is the current Chair of the International Society of Paediatric Oncology-Europe Brain Tumour group and a prominent member of the National Children's Cancer and Leaukaemia Group Dr. Pizer has an interest in tumours of the central nervous system in children, specifically centering on medulloblastoma, neuroblastoma, and the development of markers of infection in oncology.
Dr. Richard Grundy is a Professor of Paediatric Neuro-Oncology and Cancer Biology in the Faculty of Medicine and Health Sciences at the University of Nottingham, UK. He is the Chair of the Biology Committee of the UK Paediatric Brain Tumour Consortium and the Chief Investigator of the International Society of Paediatric Oncology ependymoma study. Dr. Grundy's current research focuses to elucidate the underlying molecular alterations of specific tumour types for the development of new drug therapies. His work includes the use of DNA and RNA microarray technologies to identify biological correlates of tumour behavior. Dr. Grundy also has an active interest in the development and conduct of clinical trials in CNS tumours.
Dr. Alexandre Vasiljevic is a Neuropathologist in the Department of Pathology and Neuropathology of the East Hospitals in Lyon, France. He is also an Associate Professor of Anatomic Pathology at Université Claude Bernard in Lyon, France. He co-manages the French Registry of Tumours of the Pineal Region. Dr. Vasiljevic's main interests include paediatric brain tumours, developmental neuropathology, and pituitary pathology. For many years, his work has been focused on the pathobiology of tumours in the pineal region. He recently followed a one-year fellowship in the lab of Dr. Annie Huang, focusing on the molecular pathology of pineoblastomas.
MD, MRCP, FRCPCH
Dr. Darren specialises in paediatric neuro-oncology (tumours of the brain and spine) and the development of new anti-cancer drugs for children and adolescents. He trained in the UK and Canada and is a member of both national and international groups in the fields of paediatric neuro-oncology and drug development. He is the current Chair of the Children’s Novel Agents Subgroup of the UK NCRI and was the previous Chair of the European SIOPE High Grade Glioma working group and remains an active member of both the SIOPE High and Low Grade Glioma working groups. He is a member of the Guy’s Complex NF1 clinic. He sits on the ITCC Clinical Trials Committee and is a Chief Investigator of over 15 completed, on-going and planned clinical trials in paediatric cancer. His research interests include: the biology of childhood brain tumours, the use of innovative imaging techniques in childhood cancer and drug development of targeted therapies in childhood and adolescent oncology.